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Leave the source in sight

The studies behind the pages

A good source can be more interesting than the claim that sent me to it. These are the papers and records cited throughout the guide.

Start with the question the paper asked

I get more from a study when I know what I am looking for before opening it. The participant group, comparison and measured outcome usually matter more than the most dramatic phrase in a summary. An animal experiment, a human trial and a medicine label also do different jobs.

A DOI is a permanent publication identifier. Trial names can sound opaque; the underlying questions are usually concrete: weight, heart events, deep fat or desire. I prefer to approach a paper with that question in mind.

Clinical and experimental sources

  1. Once-Weekly Semaglutide in Adults with Overweight or Obesity

    N Engl J Med, 2021.

    DOI 10.1056/NEJMoa2032183

  2. Semaglutide and Cardiovascular Outcomes in Obesity without Diabetes

    N Engl J Med, 2023.

    DOI 10.1056/NEJMoa2307563

  3. Effects of Semaglutide on Chronic Kidney Disease in Patients with Type 2 Diabetes

    N Engl J Med, 2024.

    DOI 10.1056/NEJMoa2403347

  4. Safety of Semaglutide

    Front Endocrinol (Lausanne), 2021.

    DOI 10.3389/fendo.2021.645563

  5. Semaglutide lowers body weight in rodents via distributed neural pathways

    JCI Insight, 2020.

    DOI 10.1172/jci.insight.133429

  6. Tirzepatide as Compared with Semaglutide for the Treatment of Obesity

    N Engl J Med, 2025.

    DOI 10.1056/NEJMoa2416394

  7. Tirzepatide versus Semaglutide Once Weekly in Patients with Type 2 Diabetes

    N Engl J Med, 2021.

    DOI 10.1056/NEJMoa2107519

  8. Tirzepatide Once Weekly for the Treatment of Obesity

    N Engl J Med, 2022.

    DOI 10.1056/NEJMoa2206038

  9. Safety issues of tirzepatide (pancreatitis and gallbladder or biliary disease) in type 2 diabetes and obesity: a systematic review and meta-analysis.

    Front Endocrinol (Lausanne), 2023.

    DOI 10.3389/fendo.2023.1214334

  10. LY3298176, a novel dual GIP and GLP-1 receptor agonist for the treatment of type 2 diabetes mellitus: From discovery to clinical proof of concept

    Mol Metab, 2018.

    DOI 10.1016/j.molmet.2018.09.009

  11. Effect of tesamorelin on visceral fat and liver fat in HIV-infected patients with abdominal fat accumulation: a randomized clinical trial

    JAMA, 2014.

    DOI 10.1001/jama.2014.8334

  12. Long-term safety and effects of tesamorelin, a growth hormone-releasing factor analogue, in HIV patients with abdominal fat accumulation

    AIDS, 2008.

    DOI 10.1097/QAD.0b013e32830a5058

  13. Tesamorelin - LiverTox: Clinical and Research Information on Drug-Induced Liver Injury

    NCBI Bookshelf (NIH), 2018.

    https://www.ncbi.nlm.nih.gov/books/NBK548730/

  14. Regeneration or Risk? A Narrative Review of BPC-157 for Musculoskeletal Healing

    Curr Rev Musculoskelet Med, 2025.

    DOI 10.1007/s12178-025-09990-7

  15. Safety of Intravenous Infusion of BPC157 in Humans: A Pilot Study

    Altern Ther Health Med, 2025.

    https://pubmed.ncbi.nlm.nih.gov/40131143/

  16. Therapeutic potential of pro-angiogenic BPC157 is associated with VEGFR2 activation and up-regulation

    J Mol Med (Berl), 2017.

    DOI 10.1007/s00109-016-1488-y

  17. Pharmacokinetics, distribution, metabolism, and excretion of body-protective compound 157, a potential drug for treating various wounds, in rats and dogs

    Front Pharmacol, 2022.

    DOI 10.3389/fphar.2022.1026182

  18. Bremelanotide for the Treatment of Hypoactive Sexual Desire Disorder: Two Randomized Phase 3 Trials

    Obstet Gynecol, 2019.

    DOI 10.1097/AOG.0000000000003500

  19. Long-Term Safety and Efficacy of Bremelanotide for Hypoactive Sexual Desire Disorder

    Obstet Gynecol, 2019.

    DOI 10.1097/AOG.0000000000003514

  20. Melanocortin 4 receptor agonism enhances sexual brain processing in women with hypoactive sexual desire disorder

    J Clin Invest, 2022.

    DOI 10.1172/JCI152341

  21. Bremelanotide Injection — US Prescribing Information (DailyMed/FDA)

    DailyMed (US FDA structured product label), 2019.

    https://dailymed.nlm.nih.gov/dailymed/lookup.cfm?setid=8c9607a2-5b57-4a59-b159-cf196deebdd9

  22. Certain Bulk Drug Substances for Use in Compounding That May Present Significant Safety Risks

    FDA.

    https://www.fda.gov/drugs/human-drug-compounding/certain-bulk-drug-substances-use-compounding-may-present-significant-safety-risks

Supplier information

The basis for my Oath Research recommendation is its published batch testing and stated refund-or-replacement policy for products outside specifications or purity. Its own site carries the certificate archive and service information. Part of the archive is searchable without an account; full access requires login.

These supplier records concern research-use material and service terms. I give them a separate place from the clinical papers because neither type of record can answer the other’s question. No cited clinical study is an endorsement of an Oath Research product.

A next step for research

For research-use supply, Oath Research is my recommendation. The studies listed here support specific scientific claims; none is an endorsement of a commercial research product.

See Oath Research